Computational Toxicology

Guest: Dr. Nicole Kleinstreuer, Director, Computational Toxicology Group, Integrated Laboratory Systems, Inc. (contractor to National Toxicology Program Interagency Center for Evaluation of Alternative Methods (NICEATM))
Topics: Computational toxicology, predictive modeling methods in toxicology


Dr. Nicole Kleinstreuer


A Computational Model Predicting Disruption of Blood Vessel Development, PLOS Computational Biology, April 4, 2013

NICEATM website

NICEATM Support of the Tox21 Program


Tox21 NTP site

Click to Download: Radio In Vivo November 25, 2015

Science PIO

Guest: Matt Shipman, Research Communications Lead, University Communications, North Carolina State University
Topics: Matt’s new book, Handbook for Science Public Information Officers, Matt’s career, science writing and communications


Matt Shipman


Communication Breakdown, Matt’s blog

Matt’s LinkedIn page

NCSU press releases written by Matt

Click to Download: Radio In Vivo November 11, 2015

Nobel Laureate Dr. Oliver Smithies

Guest: Dr. Oliver Smithies, Weatherspoon Eminent Distinguished Professor, Department of Pathology and Laboratory Medicine, UNC School of Medicine, winner of the 2007 Nobel Prize in Physiology or Medicine
Topics: Dr. Smithies’ distinguished career in science, his childhood, educational background, and outside interests; working with his wife, Dr. Nobuyu Maeda; gene targeting, gel electrophoresis, current work on pre-eclampsia


Dr. Oliver Smithies


Dr. Smithies’ DPLM faculty profile

Dr. Maeda’s DPLM faculty profile

2007 UNC news release, “Oliver Smithies wins Nobel Prize”

Dr. Smithies’ Nobel lecture, December 7, 2007

Click to Download: Radio In Vivo October 28, 2015


Guests: Dr. Charles Nunn, Director, TriCEM; Professor, Evolutionary Anthropology and Global Health, Duke University; Dr. Craig McClain, Deputy Director, TriCEM; Founder and Chief Editor, Deep Sea News
Topics: Rolling out TriCEM to the Triangle science community, succeeding NESCent; Charlie’s research on mammalian sleep; Craig’s oceanographic research, adventures, and his new blog, The Science of the South


TriCEM: Triangle Center for Evolutionary Medicine

NESCent reference site

Nunn laboratory site

Craig’s website

Click to Download: Radio In Vivo October 14, 2015


Dr. Charles Nunn


Dr. Craig McClain

Nanotechnology in Drug Delivery

Guest: Dr. Alexander “Sasha” Kabanov, Mescal Swaim Ferguson Distinguished Professor, Director, Center for Nanotechnology in Drug Delivery, UNC Eshelman School of Pharmacy; Co-Director, Carolina Institute for Nanomedicine, UNC-Chapel Hill
Topics: Novel nanomedicines and engineered cellular therapies for cancer, stroke, neurodegenerative disorders, and other diseases; nanotechnology in drug delivery; new training program to grow cancer nanotechnology work force


Dr. Alexander “Sasha” Kabanov


Sasha’s UNC Eshelman School of Pharmacy faculty page

Kabanov Lab

UNC Center for Nanotechnology in Drug Delivery

Carolina Institute for Nanomedicine

Click to Download: Radio In Vivo September 30, 2015

Alzheimer’s and Immune Suppression

Guest: Dr. Carol Colton, Professor of Neurology, Duke University Medical Center
Topics: The immune system and Alzheimer’s disease, arginine deprivation, microglia, inflammation and immune suppression in the brain


Dr. Carol Colton


Carol’s Duke Department of Neurology faculty page

“Arginine Deprivation and Immune Suppression in a Mouse Model of Alzheimer’s Disease” – Journal of Neuroscience

Click to Download: Radio In Vivo August 12, 2015


Guest: Dr. Kathleen Caron, Professor and Chair, Department of Cell Biology and Physiology, UNC-Chapel Hill School of Medicine
Topics: Adrenomedullin – a potent vasodilator, and its role in preeclampsia, normal and abnormal pregnancy, fertility, and placental development, cardiovascular health, cancer, and the lymphatic vascular system; mentoring


Dr. Kathleen Caron


Kathleen’s Department of Cell Biology and Physiology faculty page

Caron Lab Research

Adrenomedullin and Pregnancy: Perspectives from Animal Models to Humans

Click to Download: Radio In Vivo July 29, 2015

Pharmacogenetic Testing

Guest: Jivan Moaddeb, Pharm.D., clinical pharmacist, Center for Applied Genomics & Precision Medicine, Duke University School of Medicine
Topics: Pharmacogenetic testing, clinical implementation of pharmacogenomics, patient adherence, medication therapy management


Dr. Jivan Moaddeb


The Haga Group (Dr. Susanne Haga, Dr. Jivan Moaddeb) home page

Publications authored by Jivan Moaddeb

Pharmacogenetic testing: current evidence of clinical utility

The potential impact of pharmacogenetic testing on medication adherence

Click to Download: Radio In Vivo July 1, 2015

Microbiome & Probiotics

Guest: Dr. Andrea Azcarate-Peril, Assistant Professor, Department of Cell Biology; Director, Microbiome Core Facility, UNC-Chapel Hill School of Medicine
Topics: The gut microbiome’s role in digestion and immunity, microbiomes of exclusively breastfed babies, probiotics, prebiotics and synbiotics, the microbiome and colorectal cancer, UNC Microbiome Core Facility


Dr. Andrea Azcarate-Peril


Andrea’s Dept. of Cell Biology and Physiology faculty page

Andrea’s Microbiome Core Facility Research page

UNC Medical School Microbiome Core Facility

“Breastfeeding may aid transition to solid food” Yahoo News

“Milk- and solid-feeding practices and daycare attendance are associated with differences in bacterial diversity, predominant communities, and metabolic and immune function of the infant gut microbiome” – Frontiers in Cellular and Infection Microbiology article, February 2015

“The intestinal microbiota, gastrointestinal environment and colorectal cancer: a putative role for probiotics in prevention of colorectal cancer?” – PubMed 2011 publication abstract

Click to Download: Radio In Vivo June 10, 2015