Gene therapy for Pompe disease

Guest: Dr. Dwight Koeberl, Professor of Pediatrics, Professor of Molecular Genetics and Microbiology; Medical Director, Pediatric Biochemical Genetics Laboratory, Duke University
Topics: Gene therapy clinical trial for Pompe disease, gene therapy history and current practice, enzyme replacement therapy, newborn screening, Actus Therapeutics

 

Dr. Dwight Koeberl

 

Dwight’s faculty page

ClinicalTrials.gov listing for Pompe gene therapy trial

Dr. Kishnani’s faculty page

Actus Therapeutics

“Gene therapy trial for Pompe disease begins” DCRI press release, February 5, 2019

Click to Download: Radio In Vivo April 24, 2019

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Human energy expenditures

Guest: Dr. Herman Pontzer, Associate Professor of Evolutionary Anthropology, Duke University
Topics: Evolution of human metabolism, constrained energy expenditure model, physical activity and metabolism, the science of diet & exercise, cardiometabolic health in hunter-gatherers

 

Dr. Herman Pontzer

 

Herman’s Duke faculty page

“Debunking the Hunter-Gatherer Workout” NY Times article by Herman, 2012

“The Myth of Metabolism, Exercise, and Weight Loss” AARP article by Herman

Click to Download: Radio In Vivo March 6, 2019

Clinical Trial Incentives

 

Guests: Dr. Charlene Wong, Assistant Professor of Pediatrics; Dr. Chuck Scales, Jr., Associate Professor of Surgery, Duke University School of Medicine; Co-Directors, Behavioral Research Intervention Science Center (BRISC)
Topics: BRISC, behavioral economics, clinical trial participation incentives, Dr. Wong’s health services research, Dr. Scales’s research on kidney stones

 

BRISC: Behavioral Research Intervention Science Center

Charlene’s Duke faculty page

Chuck’s Scholars@Duke page

JAMA abstract: “Return of Research Results to Study Participants: Uncharted and Untested”

Click to Download: Radio In Vivo February 13, 2019

Dr. Charlene Wong

Dr. Chuck Scales

 

Microbial communities

Guest: Dr. Manuel Kleiner, Department of Plant and Microbial Biology, NC State University
Topics: Gut microbes’ diet, microbial symbioses, metaproteomics, ecophysiology, plant root microbes

 

Dr. Manuel Kleiner

 

The Kleiner Lab: Microbial symbioses, Metaproteomics, Ecophysiology

Plant Soil Microbial Community Consortium (PSMCC)

Researchers Devise New Way to Discern What Microbes Eat

Manuel’s NCSU Plant and Microbial Biology page

Click to Download: Radio In Vivo January 16, 2019