CRISPR Gene Editing

Guest: Dr. Rodolphe Barrangou, Associate Professor, Food Science, NC State University
Topics: Gene editing system CRISPR, its history and the explosion of research in CRISPR in biotechnology, food and agriculture, translational medicine, disease modeling, gene therapy, and more

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Dr. Rodolphe Barrangou

 

NC State CRISPR Lab

Rodolphe’s faculty page, NCSU Department of Food, Bioprocessing,and Nutrition Sciences

“Steward of the Future: Rodolphe Barrangou”

CRISPR: Science Magazine’s Breakthrough of the Year, 2015

PubMed link to seminal 2007 paper, CRISPR provides acquired resistance against viruses in prokaryotes

Click to Download: Radio In Vivo May 4, 2016

DIY Biology

Guests: Mike Lisanke, Jim Rose, and Tom Randall, co-founders, TriDIYBio (Triangle DIY Biology)
Topics: TriDIYBio, DYIBio.org, Citizen Science and Jim, Tom, and Mike’s individual projects and interests

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Triangle DIY Bio

 

TriDIYBio website

DIYbio.org, the national DIY Biology organization

iGEM: the International Genetically Engineered Machine competition

Ronin Genetics: Tom’s website for his home lab

Click to Download: Radio In Vivo April 27, 2016

Brain Tumor Treatment with Stem Cells



Guests: Dr. Shawn Hingtgen, Assistant Professor, Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy; Dr. Matthew Ewend, Chair, Department of Neurological Surgery, UNC, Group Leader, NeuroOncology, UNC Lineberger Comprehensive Cancer Center
Topics: Stem cell therapies for brain cancer (glioblastoma multiforme), mouse models, real-time non-invasive imaging, clinical perspectives on brain tumor treatment

 

Hingtgen Lab

Shawn’s faculty page

Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma, (abstract), Nature Communications, February, 2016

“Meet Matthew Ewend, MD”

Scicast: Early Tumour Response from Stereotactic Radiosurgery Predicts Outcome

Click to Download: Radio In Vivo March 30, 2016

 

hingtgenphoto Dr. Shawn Hingtgen

 

 

 

 

ewendphoto2 Dr. Matthew Ewend

Bone Structure, Metabolism, & Biophysical Forces

Guest: Dr. Janet Rubin, Professor, Department of Medicine, UNC School of Medicine
Topics: Triggering bone formation from mesenchymal stem cells, mechanisms of exercise effects on bone quantity and quality

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Dr. Janet Rubin

 

Rubin Lab home page

Faculty page at Diabetes Center for Research

“Intranuclear Actin Regulates Osteogenesis” Stem Cell, September 2015

Awesome “accident” turns stem cells into bone

Click to Download: Radio In Vivo March 23, 2016

Pharmacogenomics

Guest: Dr. Tim Wiltshire, Director, Center for Pharmacogenomics and Individualized Therapy, UNC Eshelman School of Pharmacy
Topics: Pharmacogenomics, clinical implementation, pharmacy implementation, advances in the field

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                        Dr. Tim Wiltshire

 

UNC Eshelman School of Pharmacy Center for Pharmacogenomics and Individualized Therapy

Tim Wiltshire Lab

Tim’s UNC faculty page

Click to Download: Radio In Vivo March 9, 2016

Salinity Gradient Energy


Guests: Dr. Douglas Call, Assistant Professor of Civil, Construction, and Environmental Engineering, North Carolina State University; Dr. Orlando Coronell, Assistant Professor of Environmental Sciences and Engineering, UNC Gillings School of Public Health
Topics: Dr. Call and Dr. Coronell’s collaborative UNC ROI project, “Salinity Gradient Energy: An Inexhaustible Clean Energy Resource for North Carolina,” Dr. Call’s research on technologies to recover energy from unconventional sources, Dr. Coronell’s research on water treatment technologies

 

UNC ROI (Research Opportunities Initiative)

UNC ROI Awardees

The Call Lab

Coronell Research Group

Click to Download: Radio In Vivo February 3, 2016

Douglas Call Portrait

Dr. Douglas Call

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Dr. Orlando Coronell

Public Science

Guest: Dr. Holly Menninger, Director of Public Science, College of Sciences, North Carolina State University
Topics: Public science, citizen science, science literacy, science communication, CitSci 2017 (coming to Raleigh)

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Dr. Holly Menninger

 

“Dr. Holly” – Holly’s website

CitSci 2017, the Citizen Science Association conference to be held in Raleigh February 23-25, 2017

Your Wild Life

SciStarter (citizen science site)

Zooniverse (citizen science site)

Click to Download: Radio In Vivo January 13, 2016

Human Research Subject Protection

Guest: Dr. Elizabeth Kipp Campbell, Director, Office of Human Research Ethics (OHRE), UNC Chapel Hill
Topics: History of and current trends in human research subject protections, Institutional Review Boards, research ethics, UNC OHRE

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Dr. Elizabeth Kipp Campbell

 

UNC Office of Human Research Ethics

The Belmont Report: Ethical Principles and Guidelines for the Protection of Human
Subjects of Research (1979)

Click to Download: Radio In Vivo January 6, 2016 (10th anniversary episode!)

Computational Toxicology

Guest: Dr. Nicole Kleinstreuer, Director, Computational Toxicology Group, Integrated Laboratory Systems, Inc. (contractor to National Toxicology Program Interagency Center for Evaluation of Alternative Methods (NICEATM))
Topics: Computational toxicology, predictive modeling methods in toxicology

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Dr. Nicole Kleinstreuer

 

A Computational Model Predicting Disruption of Blood Vessel Development, PLOS Computational Biology, April 4, 2013

NICEATM website

NICEATM Support of the Tox21 Program

ToxCast

Tox21 NTP site

Click to Download: Radio In Vivo November 25, 2015

Science PIO

Guest: Matt Shipman, Research Communications Lead, University Communications, North Carolina State University
Topics: Matt’s new book, Handbook for Science Public Information Officers, Matt’s career, science writing and communications

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Matt Shipman

 

Communication Breakdown, Matt’s blog

Matt’s LinkedIn page

NCSU press releases written by Matt

Click to Download: Radio In Vivo November 11, 2015